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Wednesday, August 12, 2020 | History

3 edition of DNA Recombination and Repair (Frontiers in Molecular Biology) found in the catalog.

DNA Recombination and Repair (Frontiers in Molecular Biology)

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Published by Oxford University Press, USA .
Written in English


Edition Notes

ContributionsPaul J. Smith (Editor), Christopher Jones (Editor)
The Physical Object
Number of Pages256
ID Numbers
Open LibraryOL7406109M
ISBN 100199637067
ISBN 109780199637065

  Deinococcus radiodurans' extreme resistance to ionizing radiation, desiccation, and DNA-damaging chemicals involves a robust DNA repair that reassembles its shattered genome. The repair process requires diploidy and commences with an extensive exonucleolytic erosion of DNA fragments. Liberated single-stranded overhangs prime strand elongation on overlapping fragments and the Cited by: cellular mechanisms—DNA replication and DNA repair—that are responsible for keeping these changes to a minimum. Finally, we consider some of the most intriguing ways in which DNA sequences are altered by cells, with a focus on DNA recombination and the movement of special DNA sequences in our chro-mosomes called transposable elements.

This mechanism of repair only takes place only when 2 DNA double stranded (duplex) contains extensive region of homology. As a result of this, the damaged DNA can access to the homologous area of duplex DNA and does a complementary pair of base pairing. Homologous recombination repairs DNA before the cell enters M phase of mitosis.   Dna replication, repair and recombination 1. DNA REPLICATION, REPAIR AND RECOMBINATION Nanjing Foreign Language School International Centre Tutoring Club — Biology Elite Mike Chen Basic Genetic Mechanisms: Based on Molecular Biology of the Cell 6th edition 2. OBJECTIVE • How does DNA replicates itself?

This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. Homologous recombination is a major DNA repair process in bacteria. It is also important for producing genetic diversity in bacterial populations, although the process differs substantially from meiotic recombination, which repairs DNA damages and brings about diversity in eukaryotic gous recombination has been most studied and is best understood for Escherichia .


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DNA Recombination and Repair (Frontiers in Molecular Biology) Download PDF EPUB FB2

"An overview of current knowledge on DNA recombination and repair. Topics covered include DNA structure and folding dynamics, features of recognition and cleavage of signal sequences impact upon double strand break repair, strategies for dealing with DNA mismatches or lesions, the enzymology of excision repair, and the integration of DNA repair into other cellular pathways."/5(1).

This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical : Fumio Hanaoka.

Next, we discuss the cellular mechanisms—DNA replication and DNA repair—that are responsible for keeping these changes to a minimum. Finally, we consider some of the most intriguing ways in which DNA sequences are altered by cells, with a focus on DNA recombination and the movement of special DNA sequences in our chromosomes called Cited by: About this book Introduction This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their.

DNA: Recombination, Interactions and Repair presents the result of the proceedings of the FEBS Symposium on DNA, which focuses on DNA recombination in vivo and in vitro, DNA interactions, and DNA Edition: 1.

DNA Recombination and Repair In cases where DNA is severely damaged, a cell will engage in a phenomenon called the SOS response in an effort to salvage a functioning set of genetic information. This response, also called error‐prone repair, represents a last‐ditch response to salvage a chromosomal information system.

This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the “3Rs”) and the related processes, with special consciousness of their biological and clinical consequences.

ISBN: OCLC Number: Description: xix, pages: illustrations ; 25 cm: Contents: Molecular processing of DNA folding anomalies in Escherichia coli / David R.F. Leach --Double-strand break repair and V(D)J recombination / Belinda K.

Singleton and Penny A. Jeggo --Translesion replication / Christopher Lawrence and. Book: DNA replication, repair, recombination.

STUDY. PLAY. DNA replication. produces two complete double helices from the original DNA molecule, each new DNA helix identical (except for rare copying errors) in nucleotide sequence to the parental DNA double helix. Because each parental strand serves as the template for one new strand, each of.

The chapter on mutation and repair of DNA dealt mainly with small changes in DNA sequence, usually single base pairs, resulting from errors in replication or damage to DNA. The DNA sequence of a chromosome can change in large segments as well, by the processes of recombination and transposition. Recombination is the production of new DNA molecule(s) from two parental DNA.

DNA recombination — the exchange of DNA segments between homologous chromosomes — provides a mechanism for generating genetic diversity beyond that achieved by the independent assortment of chromosomes. The mechanisms of DNA repair and recombination are discussed in the second half of this by:   No short book can address all the cellular processes of DNA repair and recombination.

This publication highlights a selection of some of the issues currently at the frontiers of our understanding of these processes and consists of 8 chapters, each of which describes one of the manifold aspects in the preservation of genomic : Francis L. Martin. Homologous recombination is a molecular process that has multiple important roles in DNA metabolism, both for DNA repair and genetic variation in all forms of life lly, homologous Cited by: Recombination Repair.

Recombination repair is a mechanism for generating a functional DNA molecule from two damaged molecules. It is an essential repair process for dividing cells because a replication fork may arrive at a damaged site, such as a thymine dimer, before the excision repair system has eliminated damage.

Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair, Volumethe latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.

S.M. Rosenberg, P.J. Hastings, in Encyclopedia of Genetics, DNA repair and recombination protein RuvC of Escherichia coli is an endonuclease that cleaves crossed-strand junctions in DNA intermediates in recombination.

It is specific for four-strand or Holliday junctions (named for Robin Holliday, who proposed them in an early recombination model (Holliday, ); see Holliday's Model.

As part of a large scale analysis of protein-protein interactions, known proteins implicated in replication, nucleotide excision repair, mismatch repair, base excision repair, non-homologous end joining, homologous recombination and checkpoint pathways were used in yeast 2-hybrid experiments to identify physical interactors in the predicted.

DNA Replication, Recombination, and Repair | This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences.

Meiotic recombination, the characteristics that distinguish it from recombinational repair, and effects of its dysregulation (e.g., aneuploidy) are also covered in depth.

This volume is an indispensable reference for biochemists, molecular biologists, and cell biologists who want to understand how DNA recombination maintains genomic integrity.

“This book covers important aspects of the eukaryotic response to genomic insults and the most recent and advanced protocols on DNA repair, recombination, and replication.

The intended audience is researchers in the field of DNA repair. DNA repair is the term used to describe the numerous processes of the cell that are responsible for repairing damaged DNA and maintaining genome stability.

Homologous Recombination is the transfer of genetic material between similar DNA sequences that contributes to an increase in genetic diversity. The enzymes of the homologous recombination pathway promote faithful chromosome segregation.

This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of Brand: Springer Japan.Working with Molecular Genetics Chapter 8.

Recombination of DNA CHAPTER 8 RECOMBINATION OF DNA The previous chapter on mutation and repair of DNA dealt mainly with small changes in DNA sequence, usually single base pairs, resulting from errors in replication or damage to Size: 1MB.